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PDF: SMALL ANIMAL PET IMAGING Introduction Positron emitting ...

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Source: pet.radiology.uiowa.edu // Topic: Animal Pet
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Short Desciption: importance in small animal PET is difficult to resolve,. 1. we will discuss some of. the challenges to small animal PET imaging and describe the trade-offs ...

Content Inside: November 30, 2003 13:2 WSPC/Trim Size: 9in x 6in for Proceedings miller-rouze-hutchins SMALL ANIMAL PET IMAGING M. A. MILLER, N. C. ROUZE AND G. D. HUTCHINS Indiana Center of Excellence in Biomedical Imaging Department of Radiology Indiana University School of Medicine 950 West Walnut, R2 E124 Indianapolis, IN 46202 E-mail: gdhutchi@iupui.edu As the methods and technology of positron emission tomography (PET) imaging have advanced, they have been applied not only to human clinical imaging, but to small research animals as well. Imaging small objects pushes the spatial resolution and sensitivity limits of current PET technology. We summarize the challenges presented in pushing these resolution limits without giving up sensitivity. Detector size is the current practical factor limiting resolution. Sensitivity is limited by detector characteristics and acquisition rate limits. Current scanners are capable of imaging small animals at the whole organ level. Very high resolution images can only be reached with large tracer doses and long data acquisition


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