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PDF: Aspirin Therapy in Diabetes is Underutilized

Download 4 times Source: care.diabetesjournals.org // Topic: Drugs File Size: 42.29 kb // Total of Page: 2 Page(s) Last download by rickdrakon Last download on: 1 month ago Share this info: Sample of page (click to enlarge) Short Desciption: aspirin therapy? In this issue of Diabetes Care, Rolka et. al. (6) have addressed these two ... vidual in the study was eligible for aspirin. therapy. ... Content Inside: EDITORIAL Aspirin Therapy in Diabetes is Underutilized I n 1997, the American Diabetes Association (ADA) recommended low-dose aspirin therapy as a secondary prevention strategy in people with diabetes (1,2). There was nothing that was unique in this policy. It simply formalized recommendations that were supported by meta-analyses of all secondary prevention antiplatelet trials before 1994 (3). The ADA, however, agreed that this sole strategy was not sufficient for people with diabetes. Cardiovascular events are increased at least two- to fourfold in diabetes, and the major mode of death is a cardiovascular event. The cardiovascular risk for a person with type 2 diabetes who has not had a recognized myocardial infarction is the same as a nondiabetic individual who has already had a heart attack (4). People with diabetes have platelets that are hypersensitive to aggreg a t i n g agents in vitro, and there is increased platelet thromboxane synthesis that is blocked by